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目的 探讨耳穴压豆联合腹部扭转运动对脑深部电刺激术（DBS）术后帕金森病（PD）患者便秘的效果。方法 选取2024年3月—12月在山东大学附属山东省立第三医院神经外科行DBS且出院后居家或社区康复的102例PD患者为研究对象，采用随机数字表法分为对照组和观察组，各51例。对照组给予常规宣教，观察组在对照组基础上给予耳穴压豆联合腹部扭转运动治疗。采用结肠传输试验、便秘严重程度评分量表（CSS）、简易8项帕金森病调查表（PDQ-8）比较两组治疗前后结肠动力功能、便秘症状及疗效、生活质量；比较两组治疗前后血清炎症因子C反应蛋白（CRP）、白细胞介素6(IL-6)、降钙素原（PCT）水平。结果 治疗后，观察组结肠传输试验积分、CSS评分、PDQ-8评分及血清CPR、IL-6水平均低于对照组，便秘治疗有效率高于对照组（P均<0.05）。结论 耳穴压豆联合腹部扭转运动能够增强DBS术后PD患者结肠动力功能，缓解便秘严重程度，改善肠道局部炎症反应，提升患者生活质量。
Abstract：Objective To explore the effects of traditional Chinese medicine auricular acupressure combined with abdominal rotation exercise on constipation in patients with Parkinson's disease(PD) after deep brain stimulation(DBS) surgery. Methods A total of 102 PD patients who underwent DBS in the Department of Neurosurgery of Shandong Provincial Third Hospital Affiliated to Shandong University and were discharged for home or community rehabilitation from March 2024 to December 2024 were selected as the research subjects. They were randomly divided into the control group and the observation group by random number table method, with 51 cases in each group. The control group was given routine education, while the observation group was treated with traditional Chinese medicine auricular acupressure combined with abdominal rotation exercise on the basis of the control group. The colonic transit test, constipation severity score scale(CSS), and simple 8-item Parkinson's disease questionnaire(PDQ-8) were used to compare the colonic motility function, constipation symptoms, efficacy, and quality of life before and after treatment in the two groups. The levels of inflammatory factors C-reactive protein(CRP), interleukin-6(IL-6), and procalcitonin(PCT) before and after treatment were compared between the two groups. Results After treatment, the colonic transit test scores, CSS scores, PDQ-8 scores, and serum CRP and IL-6 levels in the observation group were lower than those in the control group, and the effective rate of constipation treatment was higher than that in the control group(all P < 0. 05). Conclusion Traditional Chinese medicine auricular acupressure combined with abdominal rotation exercise can enhance colonic motility function in PD patients after DBS, alleviate the severity of constipation, improve local intestinal inflammatory response, and improve the quality of life of patients.
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基本信息:
DOI：
中图分类号:R742.5
引用信息:
[1]刘晓晨,朱珊珊,常筱洁,等.耳穴压豆联合腹部扭转运动对脑深部电刺激术后帕金森病患者便秘的疗效[J].老年医学研究,2025,6(04):23-27.
基金信息:
山东省基层卫生协会科技创新计划项目(JCK24018,耳穴压豆联合腹部扭转运动对脑深部电刺激术后帕金森病患者便秘的效果研究); 山东省医药卫生科技项目(202304041276,脑深部电刺激术后帕金森病患者非运症状发展轨迹的纵向研究)